Navigating the World of Over-The Counter (OTC) Medicines: What Medication is Best for Heartburn (in no particular order)
Written By: Mark Rogers, Pharm. D Proton Pump Inhibitors (PPIs) The drugs available as OTC in this category includes the brands Prilosec, Nexium, Protonix (I recommend buying the generic equivalent to save $$). PPIs are the most effective heartburn drugs available OTC, but with a few caveats. They require a day or two to reach full effect & provide significant relief. As such, they should be taken on a routine basis, not just as needed